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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD226
All Species:
23.03
Human Site:
Y322
Identified Species:
72.38
UniProt:
Q15762
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15762
NP_006557.2
336
38584
Y322
D
D
T
R
E
D
I
Y
V
N
Y
P
T
F
S
Chimpanzee
Pan troglodytes
XP_523966
336
38653
Y322
D
D
T
R
E
D
I
Y
V
N
Y
P
T
F
S
Rhesus Macaque
Macaca mulatta
O18906
336
38513
Y322
D
D
T
R
E
D
I
Y
V
N
Y
P
T
F
S
Dog
Lupus familis
XP_851505
381
42861
Y367
D
G
A
T
E
D
V
Y
V
N
Y
P
A
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4F0
333
38044
Y319
D
D
E
K
E
D
I
Y
V
N
Y
P
T
F
S
Rat
Rattus norvegicus
NP_001100840
346
39588
Y332
D
D
E
K
E
D
I
Y
V
N
Y
P
T
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506322
180
20286
M167
G
V
M
L
N
D
E
M
Q
G
E
N
M
N
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074115
344
38910
Y330
R
A
K
D
K
E
I
Y
M
N
F
Q
I
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
93.4
58.5
N.A.
53.8
50.8
N.A.
26.1
N.A.
N.A.
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
96.1
69.5
N.A.
69
66.7
N.A.
39.8
N.A.
N.A.
45.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
86.6
86.6
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
13
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
63
0
13
0
88
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
0
75
13
13
0
0
0
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
75
0
% F
% Gly:
13
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
75
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
13
25
13
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
13
0
0
0
0
13
13
0
0
0
13
0
13
% M
% Asn:
0
0
0
0
13
0
0
0
0
88
0
13
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
13
0
0
0
% Q
% Arg:
13
0
0
38
0
0
0
0
0
0
0
0
0
0
13
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% S
% Thr:
0
0
38
13
0
0
0
0
0
0
0
0
63
0
0
% T
% Val:
0
13
0
0
0
0
13
0
75
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
88
0
0
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _